19. January 2011 · Comments Off on The First Cryonics Newsletter · Categories: Cryonics

The cryonics movement is often thought to have been launched with the publication of Robert Ettinger’s The Prospect of Immortality by Doubleday, which occurred on June 5, 1964. Before that, however, there was a fledgling cryonics movement (though the term “cryonics” itself would not be coined until August 1965). The driving force behind this first, public foray into the physical struggle for immortality was an enigmatic figure named Evan Cooper, who would eventually be lost at sea shortly after he had destroyed his private papers.

Cooper, who was born in 1926, began to think about the freezing idea sometime around 1957, and over the next five years completed a short book, Immortality Physically, Scientifically, Now (PDF) which was privately circulated in a small quantity late in 1962. Sometime in the next six months he heard of Ettinger’s independent efforts, which had resulted in a preliminary version of Prospect around the time Cooper finished his book, and the two corresponded. Word was received of Doubleday’s intentions to publish an expanded version of Ettinger’s book, and plans were laid for an organized effort to promote the idea. The first organizational meeting (which saw the creation of the Life Extension Society or LES), was to coincide as far as possible with publication of the book. But delay in the publication led to the meeting being held some months earlier, Dec. 28-29, 1963, in Washington, D.C., where Ev Cooper lived. This was followed by the first issue of the first newsletter devoted to the freezing idea, which was dated January 1964 and bore the title, Life Extension Society Newsletter. Three pages in length, it mainly dealt, as might be expected, with the conference that had just been held and the organization that was formed as a consequence. In January the following year the title would metamorphose to the inspiring imperative, Freeze-Wait-Reanimate, where it remained.

For over two years LESN/FWR was the only newsletter devoted to the cryonics idea, and it endured for several more years, until issue no. 60 dated September 1969. Many important events would be chronicled in its pages, including the successes with revival of frozen cat brains (September 1965 and later), the wild cryonics conference in early 1966, the first human freezing later that year, and the first freezing under controlled conditions, that of James Bedford in 1967. For awhile the newsletter enjoyed a huge success, with circulation said to number around 1,000—quite a generous figure even by today’s (2011) standards. This however would not continue for long. LES was beset with problems which became increasingly severe as interest in it waned and volunteer help became scarce. When it effectively shut down the newsletter died with it, its issues remaining as an important legacy of early cryonics history.

The complete back issues of the Life Extension Society Newsletter and Freeze-Wait-Reanimate are available in PDF (400 MB) here.

From “For The Record,” Cryonics, December 1990, updated by the author, January 2011.

27. December 2010 · Comments Off on Is a life worth starting? Some personal views · Categories: Arts & Living, Cryonics, Death, Science · Tags: , , , , , ,

For life—the life of any sentient creature—to be worth living, there must, as Robert Ettinger has often said, be a preponderance of satisfaction over dissatisfaction. If this overall slant toward good rather than bad is maintained, it seems reasonable that one stands to gain by continued existence. I am not sure what fraction of the human (or other sentient) population achieves this positive balance and will not speculate except to note that by appearances there are many humans who do achieve it, along with other creatures, pets in particular, so at least for them, life is worth continuing. To say that life once started is worth continuing does not, as David Benatar points out, imply that it was worth starting in the first place, or should have been started. But I think that, barring certain problematic cases,  it is fair to conclude that a human life at least is worth starting, if there are responsible prospective parents who would like to start it. Here I think it is reasonable to expect that the resulting person will feel that life is overall a benefit, and additionally, that others, the parents in particular, will stand to gain from the new life that has entered their lives. I don’t accept Benatar’s arguments that by and large life is pretty terrible and people delude themselves who think otherwise.

Also I reject his “asymmetry” argument, that it is “good” if a life that would be bad does not come into existence, but merely “not good” rather than “bad” if a life that would be good does not come into existence. (It is easy to see how this asymmetry supports the argument that life should not start in the first place and Benatar refers to it often.) Benatar’s main rationale for this argument seems to be that, while we would consider someone morally at fault for deliberately bringing into existence someone who would be miserable and just want to die, we would not similarly hold someone culpable who elected not to bring into existence someone who would be happy and want to remain alive. This I think should not be the only consideration, for it is based only on the idea of when we should regard an action as bad, and not at all on when we should regard it as good and commendable. (Why this particular asymmetry?) Instead, weighing both sides of the issue as I think is justified, I would opt for the fully symmetric position that it is “not bad” if a life that would be bad does not come into existence, and similarly, “not good” if a life that would be good does not come into existence. On the other hand, I question and doubt whether a life that comes into existence would be bad in the long run, given the prospect of immortality, which I think is a possibility through science (see below).

Life does, of course, have its problems, death in particular, that might call in question whether it is worthwhile after all and thus, whether the life of any sentient being is worth starting.  For this one problem there are a number of possible answers that will be satisfying to different people, and thus can serve as ground for a feeling that life is worthwhile and was worth starting despite one’s own mortality. There is the famous Epicurean argument that death is not really a problem because before it happens it causes no harm, and after it happens there is no victim. There is the Buddhist argument that, more fundamentally, the self is an illusion anyway, so that in fact no persons exist and death never really happens, though bliss can still occur through states of enlightenment which thus are worth seeking. There are various religious traditions that promise an afterlife and a happy immortality for those who prove worthy, or, in some versions, all who are born. Then there is scientific immortalism, which holds that at least substantial life extension through science and technology is possible, so that, irrespective of any supernatural or mystical process, persons of today have more to hope for as they get older than the usual biological ruin and oblivion.

The scientific possibilities for overcoming death come in different varieties that each have their own advocates. Some of these hopefuls, particularly younger ones, focus on the prospect that aging and now-terminal illnesses will be remedied in their natural lifetime, so that they will escape clinical death and need not specially prepare for it. Others who are not so confident have made arrangements for cryopreservation after clinical death, in hopes of resuscitation and cure of aging and diseases when the requisite technology becomes available. Still others hold out for advances on a more cosmic scale that will eventually make it possible to raise the dead comprehensively. (Some possible scenarios for this using multiple, parallel time streams rather than revisiting or recovering a hidden past are considered in my book, Forever for All, and the article at http://www.universalimmortalism.org/resurrection.htm.) The three possibilities are not mutually exclusive, so that, for example, persons who have chosen cryonics may also place varying hopes in the other two. In fact, my personal viewpoint as a scientific immortalist grants some validity to all three possibilities, but I think it is imperative now to be engaged in cryonics, which is almost unique and the clear favorite as a proactive, interventive strategy against death. Passive acceptance of the dying process simply does not feel right, whatever the prospects for near-term medical progress, or on the other hand, resurrections in a more distant, technologically superior future. It goes without saying that I also think future life will be worth living—it should be possible to make it so, if future developments can provide the opportunity.

Review of  Better Never to Have Been: The Harm of Coming into Existence by David Benatar. New York: Oxford University Press, 2006

“Would that I had never been born” is a lament sometimes voiced in the depth of misfortune, a cry of despair we hope may be soon be stilled by something more positive, when the bad things, whatever they are, have run their course. Enter David Benatar, a respected professor of philosophy at the University of Cape Town, South Africa. In the volume here reviewed he offers the extreme view that in fact it would have been better, all things considered, if not one of us had ever existed, or even any sentient life whatever. Life is that bad, he says, and he bases this judgment on certain logical principles along with empirical evidence of the allegedly poor quality of life that most of us are forced to endure in this world. Among the consequences is that no more humans should be born, and the human race (and other sentient creatures) ought to become extinct.

Antinatalism—the viewpoint that birth of sentient life, human in particular, is bad and ought not to happen, is a recurring one theme history, a noted proponent being the philosopher Arthur Schopenhauer (1788-1860). It can also be founded, as Benatar proposes, on certain assumptions considered reasonable by many people today, particularly those of a scientific, materialist outlook who are not inclined to over-optimism. Among the assumptions are that anyone’s life, overall, is an exercise in futility. Death—eternal oblivion—is the eventual fate of each person, and will happen through the normal aging process if not sooner. (Thus there is no serious prospect of a religious afterlife. Though not stated in the book, it is clear also that radical life extension, whether by imminent medical breakthroughs or through an initial “holding action” such as cryonics, is discounted.) Moreover, the human species will eventually die out, as is the fate of all biological species, so the extinction advocated by Benatar must happen in the end regardless. Another important presumption, in this case justified at length, is that in most people’s lives sorrow and misery predominate heavily over joy and happiness, so that their lives are not worth living.

Benatar denies that any good is done in any act of procreation, even if the life of the offspring is predominantly happy and if that person expresses gratitude for having been given life. The very best that could happen, Benatar says, is that no harm would be done, but only if the offspring never experienced anything bad in his/her entire life, an unlikely prospect. Even then, no good would be done or moral credit accrue in bringing that person into existence—good is done only in not bringing into existence any person who, in the course of his/her life, would at least experience some amount of bad. Harm is done, and in any likely circumstance, unacceptably serious harm, in bringing anyone into the world.

Such arguments seem unpersuasive for any of a number of reasons, and many will also find them offensive. In the matter of family planning, the prospective parents will be motivated by thoughts such as a child would bring them joy even as they in turn strive to provide the child with a happy home life and a good upbringing. Overall the child can be expected to be grateful both during the period of childhood and later in life, something that seems borne out in practice, even if hardship also occurs. As tough as the going may be at times, most people do not feel their parents were morally at fault for having had them, and are not ready to end their lives over any perceived shortcomings in their present situation or future prospects.

Benatar devotes a chapter of his book to arguing, nonetheless, that actually life as most people live it is very bad, suggesting that those who disagree don’t realize just how bad it is and are suffering some kind of delusion. But this begs the question of who is to judge. Turning the argument around, is it not possible that Benatar himself is suffering from depression that clouds his judgment? Natural selection of course favors a brighter outlook: Benatar’s thinking is not conducive to reproductive fitness. Beyond that, it is hard to see that his point of view is more “logical” than a more life-affirming one, both being based, when the rhetoric has run its course, on basic gut feelings about what is pleasant or worthwhile or isn’t, in what relative amounts, and how the mix that occurs in life should be assessed.

Despite life’s alleged wretchedness, Benatar himself is not ready to commit suicide but insists that life once started, his in particular, may be worth continuing even if it should not have been started in the first place. (Sometimes this sort of argument is reasonable. A woman should not be raped, but a child born as a consequence should not be killed.) More generally Benatar’s stance is passive rather than proactive: having children should be legal, even though no one should have them, much as we might favor allowing smoking even though it is medically and socially inadvisable.

Benatar is aware that, despite these limited concessions, his stance will be unpopular and devotes much attention to defending it against various possible lines of attack. Still it is doubtful his arguments will persuade many who are not already strongly leaning his way. The rest of us, surely a robust majority of humanity, will find our varied reasons to demur. Religious people will argue that life is a gift of God, children are a blessing, hardships and sorrows happen but can and will be remedied, all will be well in the end. Secular humanists and others of scientific bent may believe with Benatar that their lives must permanently end, and even accept the eventual extinction of all earthly life, yet still remain optimistic, one of their arguments being that “since life is finite, even sometimes very short, each moment of life, handled rightly, is precious.” Scientific immortalists who are hoping for radical life extension will also discount Benatar’s pessimism, though possibly in an odd way supporting the end of the present human species—in this case, however, by replacing it with something better that includes themselves in an enhanced form.

Meanwhile, an antinatalist movement has grown up that has simple, passive annihilation of the human species as its goal, endeavoring as far as possible to discourage everyone from having more children. In addition to a claimed humanitarian purpose—eliminating suffering as Benatar proposes—there is an environmental motive some endorse, arguing that the earth’s biosphere would greatly benefit if there were no humans to befoul it, as they generally do. Potentially a conflict could erupt between antinatalists and immortalists, who hope to be in the world for a very long time. My feeling, though, is that the antinatalist movement is both unpopular and self-limiting—on both counts, natural selection so wills it. Immortalists in any case are not so much trying to populate the planet as trying to endure as individuals. So probably we should not worry too much. Instead let’s talk to these people. Some of them (Benatar included?) may be willing to rethink their position.

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About the author: David Benatar is professor of philosophy and head of the Department of Philosophy at the University of Cape Town in Cape Town, South Africa. Though best known for his advocacy of antinatalism in his book Better Never to Have Been, he is also the author of a series of widely cited papers in medical ethics. His work has appeared in such journals as Ethics, Journal of Applied Philosophy, Social Theory and Practice, American Philosophical Quarterly, QJM: An International Journal of Medicine, Journal of Law and Religion and the British Medical Journal.

09. August 2010 · Comments Off on Ken Hayworth on straight freezing in cryonics · Categories: Cryonics · Tags: , , , , , ,

Ken Hayworth’s idea of promoting a fixation-based alternative to brain cryopreservation is something I am highly sympathetic to overall, and I hope some progress in this direction results from the work he is doing and trying to induce others to do. That said, I wanted to comment on Hayworth’s remarks about straight freezing of brain tissue.

Figure 1B shows the horrific damage (destroyed cells) that occurs when such a slice is “preserved” using a freezing technique typical of those employed early in cryonics. Such damage is clearly irreversible by any future technology and it should come as no surprise that such techniques were flatly rejected by the scientific and medical community.

While it’s true that straight-frozen tissue as shown looks pretty awful I think it’s too strong a statement to say that “such damage is clearly irreversible by any future technology” unless you have further supporting arguments. To invoke a relevant analogy, we could run a phone book through a garden-variety shredder found in many offices, and still be able to reconstruct it from the resulting debris. The fact that there is debris remaining with the frozen tissue (as opposed to the cases of decay or burning) means we cannot, without further argument, rule out some sort of reconstructive process using future technology, including nanotechnology. It is also worth noting that with imperfect chemical fixation you run a risk of tissue loss over time that does not occur with cryopreservation; even debris resulting from straight freezing will remain as-is so long as cryogenic temperatures are maintained.

I also note that Hayworth says his proposed plastination could only be done properly if you start with a living patient with still-beating heart to distribute the initial fixative.

It is important to understand that the standard fixation and plasticization protocol is started while the animal is still alive. If the animal’s heart is allowed to stop for even a few minutes before the glutaraldehyde is perfused into the vasculature, then the quality of the preservation is markedly reduced. This fact will also be true for any whole brain protocol based on perfusion.

This of course would be problematic for any procedure to be used on humans; you’d have to treat it as some form of euthanasia.