Sociobiologist Edward O. Wilson believes that a major reason why the social sciences have made so little progress is that its practitioners have ignored the biological basis of human behavior. He is not impressed with arguments that purport that the complexities of human behavior cannot be reduced to more elemental physical principles as embodied in modern neuroscience and biochemistry. Wilson recognizes that his view on the unification of the sciences carriers forward the logical positivist ideal of the Unity of Science. In his book Consilience: The Unity of Knowledge he writes:

Logical positivism was the most valiant concerted effort ever mounted by modern philosophers. Its failure, or put more generously, its shortcoming, was caused by ignorance of how the brain works.

The canonical definition of objective scientific knowledge avidly sought by the logical positivists is not a philosophical problem nor can it be attained, as they hoped, by logical and semantic analysis. It is an empirical question that can be answered only by a continuing probe of the physical basis of the thought process itself.

Wilson is basically saying that logical positivism was not empiricist enough, a view that was anticipated by the logical empiricist Hans Reichenbach in his seminal work Experience And Prediction: An Analysis of the Foundations And the Structure of Knowledge.

On the tension between religious and scientific  perspectives of the world he writes:

The human mind evolved to believe in the gods. It did not evolve to believe in biology. Acceptance of the supernatural conveyed a great advantage throughout prehistory, when the brain was evolving. Thus it is in sharp contrast to biology, which was developed as a product of the modern age and is not underwritten by genetic algorithms. The uncomfortable truth is that the two beliefs are not factually compatible. As a result those who hunger for both intellectual and religious truth will never acquire both in full measure.

Remnants of such supernatural thinking are still with us today when we exempt humans from physical reality and attribute agency and free will to them.

Wilson is sensitive to the scenario that defective or disadvantageous genes increase and persist in modern human life but he believes that such a course of events will be relatively short-lived as humanity will master and embrace human genetic engineering. On the use of such technologies he writes:

I predict that future generations will be genetically conservative. Other than the repair of disabling defects, they will resist hereditary change. They will do so in order to save the emotions and epigenetic rules of mental development, because these elements compose the physical soul of the species. The reasoning is as follows. Alter the emotions and epigenetic rules enough, and people might in some sense be “better,” but they would no longer be human. Neutralize the elements of human nature in favor of pure rationality, and the result would be badly constructed, protein-based computers. Why should a species give up the defining core of its existence, built by millions of years of biological trial and error?

His reconciliation of human enhancement and cultural incrementalism is reminiscent of the “conservative transhumanism” of the biologist Alexis Carrel.